Charles R Ashby Selected Research

N- (4- (2- (8- cyano- 1,3a,4,9b- tetrahydro(1)benzopyrano(3,4- c)pyrrol- 2(3H)- yl)ethyl)phenyl)acetamide

11/2012	The effects of the preferential dopamine D(3) receptor antagonist S33138 on ethanol binge drinking in C57BL/6J mice.
3/2009	The preferential dopamine D3 receptor antagonist S33138 inhibits cocaine reward and cocaine-triggered relapse to drug-seeking behavior in rats.
2/2008	S33138 [N-[4-[2-[(3aS,9bR)-8-cyano-1,3a,4,9b-tetrahydro[1]-benzopyrano[3,4-c]pyrrol-2(3H)-yl)-ethyl]phenylacetamide], a preferential dopamine D3 versus D2 receptor antagonist and potential antipsychotic agent. II. A neurochemical, electrophysiological and behavioral characterization in vivo.

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Charles R Ashby Research Topics

Disease

39	Neoplasms (Cancer) 01/2022 - 11/2007
12	Hyperoxia 08/2021 - 01/2014
8	Inflammation (Inflammations) 10/2022 - 08/2013
7	Premature Birth (Birth, Premature) 10/2022 - 01/2013
7	Infections 01/2022 - 11/2008
7	Cocaine-Related Disorders (Cocaine Addiction) 02/2010 - 11/2002
6	Lung Injury 12/2021 - 01/2014
6	Colonic Neoplasms (Colon Cancer) 02/2021 - 01/2016
5	Neoplasm Metastasis (Metastasis) 01/2021 - 08/2017
5	Acute Lung Injury 10/2020 - 01/2014
5	Schizophrenia (Dementia Praecox) 12/2018 - 06/2002
4	BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia) 01/2021 - 07/2009
4	Bacterial Infections (Bacterial Infection) 01/2021 - 06/2014
4	Ventilator-Associated Pneumonia 10/2020 - 06/2014
3	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 04/2022 - 01/2018
3	Breast Neoplasms (Breast Cancer) 01/2022 - 11/2007
3	COVID-19 12/2021 - 10/2020
3	Colorectal Neoplasms (Colorectal Cancer) 07/2021 - 01/2018
3	Binge Drinking 07/2015 - 11/2012
3	Substance-Related Disorders (Drug Abuse) 01/2010 - 07/2005
2	Cystic Fibrosis (Mucoviscidosis) 09/2021 - 01/2021
2	Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome) 01/2021 - 01/2020
2	Pneumonia (Pneumonitis) 01/2021 - 01/2016
2	Prostatic Neoplasms (Prostate Cancer) 01/2021 - 05/2019
2	Carcinogenesis 01/2021 - 04/2011
2	Ovarian Neoplasms (Ovarian Cancer) 07/2019 - 01/2017
2	Obesity 01/2017 - 06/2008
2	Hypothermia 02/2008 - 01/2007
2	Catalepsy 01/2007 - 06/2005
1	Hypersensitivity (Allergy) 06/2022
1	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 06/2022
1	Sarcoma (Soft Tissue Sarcoma) 04/2022

Drug/Important Bio-Agent (IBA)

17	Pharmaceutical PreparationsIBA 10/2022 - 12/2002
14	Adenosine Triphosphate (ATP)IBA 01/2022 - 11/2007
13	ATP-Binding Cassette Transporters (ABC Transporters)IBA 02/2021 - 11/2007
11	Proteins (Proteins, Gene)FDA Link 02/2021 - 11/2007
9	HMGB1 Protein (HMG1)IBA 12/2021 - 01/2014
8	Dopamine (Intropin)FDA LinkGeneric 12/2018 - 01/2007
7	3-(2,4-dimethoxybenzylidene)anabaseineIBA 12/2021 - 06/2014
6	CytokinesIBA 12/2021 - 08/2013
6	Nicotinic Receptors (Nicotinic Acetylcholine Receptor)IBA 12/2021 - 06/2014
6	Oxygen (Dioxygen)IBA 01/2021 - 06/2014
6	AntioxidantsIBA 01/2020 - 01/2014
5	Member 2 Subfamily G ATP Binding Cassette TransporterIBA 02/2021 - 01/2016
5	Dopamine D3 ReceptorsIBA 01/2018 - 11/2002
4	ErbB Receptors (EGF Receptor)IBA 01/2022 - 11/2007
4	Mitoxantrone (Novantrone)FDA LinkGeneric 02/2021 - 11/2007
4	Member 1 Subfamily B ATP Binding Cassette TransporterIBA 01/2021 - 11/2007
4	Antineoplastic Agents (Antineoplastics)IBA 09/2015 - 10/2009
4	Cocaine (Cocaine HCl)IBA 01/2010 - 11/2002
3	dimethylacetamideIBA 10/2022 - 08/2013
3	EnzymesIBA 04/2022 - 11/2018
3	Paclitaxel (Taxol)FDA LinkGeneric 01/2021 - 03/2014
3	FlavonoidsIBA 01/2020 - 01/2017
3	LipopolysaccharidesIBA 11/2019 - 03/2015
3	EndotoxinsIBA 01/2019 - 08/2013
3	nilotinib FDA Link 01/2016 - 07/2009
3	N- (4- (2- (8- cyano- 1,3a,4,9b- tetrahydro(1)benzopyrano(3,4- c)pyrrol- 2(3H)- yl)ethyl)phenyl)acetamideIBA 11/2012 - 02/2008
3	Antipsychotic Agents (Antipsychotics)IBA 01/2007 - 06/2002
2	SolventsIBA 10/2022 - 08/2013
2	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2022 - 01/2016
2	Nicotine FDA Link 12/2021 - 01/2020
2	Heparin (Liquaemin)FDA LinkGeneric 09/2021 - 01/2021
2	Actins (F Actin)IBA 01/2021 - 01/2020
2	Doxycycline (Periostat)FDA LinkGeneric 01/2021 - 11/2008
2	Nuclear Proteins (Protein, Nuclear)IBA 10/2020 - 06/2014
2	Phosphotransferases (Kinase)IBA 02/2020 - 09/2015
2	SofosbuvirIBA 01/2020 - 01/2017
2	Ascorbic Acid (Vitamin C)FDA LinkGeneric 01/2020 - 10/2016
2	NF-kappa B (NF-kB)IBA 01/2020 - 09/2015
2	Cisplatin (Platino)FDA LinkGeneric 01/2020 - 01/2020
2	CurcuminIBA 07/2019 - 07/2019
2	PolyphenolsIBA 07/2019 - 08/2017
2	pyrimidineIBA 05/2019 - 09/2017
2	cariprazineIBA 12/2018 - 09/2018
2	Endothelin-1 (Endothelin 1)IBA 01/2018 - 01/2013
2	Silybin (Lagosa)IBA 01/2018 - 01/2017
2	elemeneIBA 09/2015 - 02/2014
2	Ethanol (Ethyl Alcohol)IBA 06/2015 - 11/2012
2	sphingosine kinaseIBA 03/2015 - 01/2013
2	bcr-abl Fusion ProteinsIBA 10/2010 - 07/2009
2	Imatinib Mesylate (Gleevec)FDA Link 10/2009 - 07/2009
2	Clozapine (Clozaril)FDA LinkGeneric 01/2007 - 01/2007
2	Apomorphine FDA Link 01/2007 - 01/2007
1	DimethylformamideIBA 10/2022
1	Excipients (Suspending Agents)IBA 10/2022
1	Asparaginase (Elspar)FDA Link 06/2022
1	sotorasibIBA 04/2022
1	ChemokinesIBA 01/2022
1	Messenger RNA (mRNA)IBA 01/2022
1	Chemokine CCL5IBA 01/2022
1	Cyclin-Dependent Kinase 4IBA 01/2022
1	Estrogen ReceptorsIBA 01/2022
1	palbociclibIBA 01/2022

Therapy/Procedure

17	Therapeutics 12/2021 - 11/2007
13	Drug Therapy (Chemotherapy) 01/2021 - 11/2002
6	Artificial Respiration (Mechanical Ventilation) 10/2020 - 01/2014
4	Self Administration (Administration, Self) 01/2010 - 07/2006
3	Chemoprevention 08/2017 - 01/2017
2	Mechanical Ventilators (Ventilator) 10/2020 - 06/2014